Catalyst-free Biginelli-type synthesis of new functionalized 4,7-dihydropyrazolo[1,5-a]pyrimidines
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چکیده
منابع مشابه
Synthesis of Some Biginelli-type Products: Nano Alumina Sulfonic acid (NASA) Catalyzed under Solvent-free Condition
Biginelli-type reaction was developed by means of a three-component condensation of analdehyde, ethyl acetoacetate, urea or thiourea and nano alumina sulfonic acid (Al2O3-SO3H)(NASA) as catalyzed. It is carried out under different conditions. In all conditions, the desiredproducts are obtained in high yields after relatively short reaction times. Nevertheless, thereactions proceeded faster and ...
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Biginelli reactions were well catalyzed on mesoporous silica MCM-41 (M41) whose activity was much greater than that of amorphous silica. Octane was the most suitable among 6 kinds of solvents examined. The addition of metal ions on M41 enhanced the catalytic activity in the order Al > Ti > Fe = In. Al-planted M41s with Si/Al ratios of 45-35 showed the highest catalytic activity and could be use...
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Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the Hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. SBA-P...
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ژورنال
عنوان ژورنال: New Journal of Chemistry
سال: 2016
ISSN: 1144-0546,1369-9261
DOI: 10.1039/c6nj00336b